Medical analysis of vitamins

SNHf is a world leader in the analysis of vitamins in biological samples for medical diagnostics. Over several decades, it has developed an expertise unique in Switzerland, in order to offer its customers and partners high added value services. Order analysis

Blood sample
  • Fasting
  • Plasma (preferably heparinized tube, but all coagulants can be used)
  • Serum (avoid haemolysis)
Quantities
  • 0.5 ml of serum or plasma for a vitamin
  • 1.0 ml of serum or plasma for 2-5 vitamins.
Packaging

Unbreakable tubes with watertight closures
Protect from light (vitamin A, carotenes, E, D, K and B2)
Name of patient, attending physician and date of collection
Please attach the order form duly and legibly filled in

Shipping

Immediately send the sample to the Institute or freeze the sample at -20 to – 80 ° C and ship it in a refrigerated packaging. Vitamin C: ship the sample frozen at -20 to – 80°C.

Download and complete the order form that you will return with the packed samples as described in the Pre-Analytic tab.

Order form
Order form

Reference interval

Vitamin Female Male
A 1061 – 2755 nmol/l 1061 – 2755 nmol/l
E 16 – 39 μmol/l 16 – 39 μmol/l
Carotenes 1774 – 5821 nmol/l 1774 – 5821 nmol/l
Folic acid 7 – 31 nmol/l 7 – 31 nmol/l
B1 10 – 53 nmol/l 10 – 53 nmol/l
B2 18 – 180 nmol/l 18 – 180 nmol/l
B6 6.5 – 69 nmol/l 10 – 111 nmol/l
B12 162 – 796 pmol/l 162 – 796 pmol/l
Biotin 3.07 – 5.12 nmol/l 3.07 – 5.12 nmol/l
C 26 – 97 μmol/l 26 – 97 μmol/l
Pantothenic acid 160 – 588 nmol/l 160 – 588 nmol/l
Niacin 198 – 905 nmol/l 198 – 905 nmol/l
K1 0.33 – 2.0 nmol/l 0.33 – 2.0 nmol/l
D 75 – 175 nmol/l 75 – 175 nmol/l

The SVI clinical trial [1] allowed the calculation of the Swiss reference intrevals of vitamins based on the analytical methods of the SVI (HPLC, chemical and microbiological) and according to the international clinical recommendations [2]. Note that for vitamins D, K and B12 the measurements are still in progress.

1. Schupbach, R., et al., Micronutrient status and intake in omnivores, vegetarians and vegans in Switzerland. Eur J Nutr. 2017 Feb;56(1):283-293
2. Geffre, A., et al., Reference Value Advisor: a new freeware set of macroinstructions to calculate reference intervals with Microsoft Excel. Vet Clin Pathol, 2011. 40(1): p. 107-12.